Target Pathogen

Loading 3D structure…

Pockets High Medium Low

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #2

0.271

Show in viewer

Surrounding area

Site 2 FPocket #6

0.231

Show in viewer

Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.827

Show in viewer

Surrounding area

Site 2 P2Rank #2

0.034

Show in viewer

Surrounding area

Residue sets

UniProt: Binding site:10-10

UniProt: Binding site:10-11

UniProt: Binding site:124-130

UniProt: Binding site:18-18

UniProt: Binding site:42-42

UniProt: Binding site:74-74

UniProt: Binding site:88-88

UniProt: Binding site:89-91

UniProt: Binding site:99-99

UniProt: Site:18-18 Transition state stabilizer

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #5

0.497

Show in viewer

Surrounding area

Site 2 FPocket #3

0.457

Likely same site as P2Rank 2 1.4 Å 17 shared residues 94% of smaller site

Show in viewer

Surrounding area

Site 3 FPocket #2

0.328

Likely same site as P2Rank 3 1.2 Å 20 shared residues 95% of smaller site

Show in viewer

Surrounding area

Site 4 FPocket #1

0.27

Likely same site as P2Rank 1 1.7 Å 16 shared residues 89% of smaller site

Show in viewer

Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.657

Likely same site as FPocket 1 1.7 Å 16 shared residues 89% of smaller site

Show in viewer

Surrounding area

Site 2 P2Rank #2

0.627

Likely same site as FPocket 3 1.4 Å 17 shared residues 94% of smaller site

Show in viewer

Surrounding area

Site 3 P2Rank #3

0.597

Likely same site as FPocket 2 1.2 Å 20 shared residues 95% of smaller site

Show in viewer

Surrounding area

Site 4 P2Rank #4

0.065

Show in viewer

Surrounding area

Site 5 P2Rank #5

0.027

Show in viewer

Surrounding area

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #1

0.457

Likely same site as P2Rank 1 1.4 Å 17 shared residues 94% of smaller site

Unusual size

Show in viewer

Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.615

Likely same site as FPocket 1 1.4 Å 17 shared residues 94% of smaller site

Show in viewer

Surrounding area

Site 2 P2Rank #2

0.008

Show in viewer

Surrounding area