Target Pathogen

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Pockets High Medium Low

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #4

0.968

Likely same site as P2Rank 1 3.3 Å 43 shared residues 88% of smaller site

Unusual size

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Surrounding area

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.982

Likely same site as FPocket 4 3.3 Å 43 shared residues 88% of smaller site

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Surrounding area

Site 2 P2Rank #2

0.602

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Surrounding area

Site 3 P2Rank #3

0.143

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Surrounding area

Residue sets

UniProt: Active site:133-133 Proton donor/acceptor

UniProt: Active site:161-161 Schiff-base intermediate with substrate

UniProt: Binding site:203-203

UniProt: Binding site:45-45

UniProt: Site:106-106 L-lysine inhibitor binding

UniProt: Site:107-107 Part of a proton relay during catalysis

UniProt: Site:44-44 Part of a proton relay during catalysis

UniProt: Site:49-49 L-lysine inhibitor binding; via carbonyl oxygen

UniProt: Site:80-80 L-lysine inhibitor binding

UniProt: Site:84-84 L-lysine inhibitor binding

No pocket predictions available for this structure.