Protein profile

HT085_RS00020

hypothetical protein

Genome: NZ_AP023069.1

Gene: WHOF_00004C NGO_0004 N776_09335 E8M63_03530 WHOF_00419 NGK_0005 TUM19854C_00040 Structure source: AlphaFold UniProt A0AA44U8S2 UniProt Q5FAI9 UniProt A0A1D3EHK9 UniProt B4RNS7
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Amino acids 147
Annotations 0
Features 7
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
HT085_RS00020
Assembly
Neisseria gonorrhoeae strain TUM19854 chromosome, complete genome
Gene
WHOF_00004C NGO_0004 N776_09335 E8M63_03530 WHOF_00419 NGK_0005 TUM19854C_00040
Status
annotated
Amino acids
147
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket Medium
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
22 147 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold HT085_RS00020
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.697

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 13.92 0.62