Protein profile

HT085_RS00110

cupin domain-containing protein

Genome: NZ_AP023069.1

Gene: TUM19854C_00180 NGK_0030 ESCNG_30029 N776_09235 E8M63_03415 WHOF_00020C WHOF_00404 Structure source: AlphaFold UniProt A0AA44ZGT2 UniProt A0A1D3EP17 UniProt B4RNV2
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Amino acids 107
Annotations 0
Features 8
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
HT085_RS00110
Assembly
Neisseria gonorrhoeae strain TUM19854 chromosome, complete genome
Gene
TUM19854C_00180 NGK_0030 ESCNG_30029 N776_09235 E8M63_03415 WHOF_00020C WHOF_00404
Status
annotated
Amino acids
107
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket High
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
41 99 Pfam PF07883 Cupin domain
41 99 InterPro IPR013096 Cupin 2, conserved barrel
7 98 CDD cd02226 cupin_YdbB-like
1 107 Gene3D G3DSA:2.60.120.10 Jelly Rolls
1 107 InterPro IPR014710 RmlC-like jelly roll fold
2 104 PANTHER PTHR36114 16.7 KDA PROTEIN IN WHIE LOCUS
2 102 SUPERFAMILY SSF51182 RmlC-like cupins
2 102 InterPro IPR011051 RmlC-like cupin domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold HT085_RS00110
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.875

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 21.54 0.812
2 0.66 0.001