Protein profile

HT085_RS00135

MJ0042-type zinc finger domain-containing protein

Genome: NZ_AP023069.1

Gene: TUM19854C_00230 WHOF_00025C NCTC11421_02902 NGK_0036 E8M63_03390 ESCNG_30024 N776_09205 NGO_0028 WHOF_00399 Structure source: AlphaFold UniProt A0AA44U8X2 UniProt Q5FAK6 UniProt A0A1D3GRW2 UniProt B4RNV8

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Amino acids 142

Annotations 0

Features 6

PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession: HT085_RS00135
Assembly: Neisseria gonorrhoeae strain TUM19854 chromosome, complete genome
Gene: TUM19854C_00230 WHOF_00025C NCTC11421_02902 NGK_0036 E8M63_03390 ESCNG_30024 N776_09205 NGO_0028 WHOF_00399
Status: annotated
Amino acids: 142
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket High

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records

Show feature table

Start	End	DB	Term	Name
118	141	Phobius	TRANSMEMBRANE	Region of a membrane-bound protein predicted to be embedded in the membrane.
119	141	TMHMM	TMhelix	Region of a membrane-bound protein predicted to be embedded in the membrane.
142	142	Phobius	CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
6	38	NCBIfam	TIGR02098	MJ0042 family finger-like domain
6	38	InterPro	IPR011723	Zinc finger/thioredoxin putative
1	117	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold HT085_RS00135	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.78