Protein profile

PA0021

hypothetical protein

Genome: NC_002516.2

Gene: PA0021 Structure source: AlphaFold UniProt Q9I7A6

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Amino acids 362

Annotations 2

Features 12

PDB binders 0

Druggability 0.647

Overview

Basic information about this protein and its source genome.

Accession: PA0021
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0021
Status: annotated
Amino acids: 362
Structure source: AlphaFold

GO:1990814 An activity that facilitates the formation of a complementary double-stranded DNA molecule. GO:0009294 The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.647

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:1990814 An activity that facilitates the formation of a complementary double-stranded DNA molecule.
GO:0009294 The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records

Show feature table

Start	End	DB	Term	Name
293	359	Gene3D	G3DSA:1.10.10.10	-
293	359	InterPro	IPR036388	Winged helix-like DNA-binding domain superfamily
5	360	PANTHER	PTHR43022	PROTEIN SMF
5	360	InterPro	IPR003488	DNA recombination-mediator protein A
297	355	Pfam	PF17782	DprA winged helix domain
297	355	InterPro	IPR041614	DprA, winged helix domain
81	283	Pfam	PF02481	DNA recombination-mediator protein A
81	283	InterPro	IPR003488	DNA recombination-mediator protein A
85	293	SUPERFAMILY	SSF102405	MCP/YpsA-like
1	292	Gene3D	G3DSA:3.40.50.450	-
75	291	NCBIfam	TIGR00732	DNA-processing protein DprA
75	291	InterPro	IPR003488	DNA recombination-mediator protein A

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0021	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.647
4				0.341