Protein profile

PA0041

hemagglutinin

Genome: NC_002516.2

Gene: PA0041 Structure source: Unavailable UniProt Q9I791
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Amino acids 3535
Annotations 1
Features 145
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
PA0041
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0041
Status
annotated
Amino acids
3535
Structure source
Unavailable
GO
GO:0003824 Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003824 Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Sequence Features

Domain/signature hits from InterPro and related databases.

145 records
Show feature table
Start End DB Term Name
3414 3520 CDD cd20727 CDI_toxin_Bp_tRNase-like
66 163 NCBIfam TIGR01901 filamentous hemagglutinin family N-terminal domain
66 163 InterPro IPR008638 Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain
11 33 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
30 291 Pfam PF05860 TPS secretion domain
30 291 InterPro IPR008638 Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain
1343 1432 Pfam PF05594 Haemagglutinin repeat
1343 1432 InterPro IPR008619 Filamentous haemagglutinin repeat
1248 1296 Pfam PF05594 Haemagglutinin repeat
1248 1296 InterPro IPR008619 Filamentous haemagglutinin repeat
296 371 Pfam PF05594 Haemagglutinin repeat
296 371 InterPro IPR008619 Filamentous haemagglutinin repeat
407 460 Pfam PF05594 Haemagglutinin repeat
407 460 InterPro IPR008619 Filamentous haemagglutinin repeat
692 769 Pfam PF05594 Haemagglutinin repeat
692 769 InterPro IPR008619 Filamentous haemagglutinin repeat
2039 2095 Pfam PF05594 Haemagglutinin repeat
2039 2095 InterPro IPR008619 Filamentous haemagglutinin repeat
471 540 Pfam PF05594 Haemagglutinin repeat
471 540 InterPro IPR008619 Filamentous haemagglutinin repeat
906 965 Pfam PF05594 Haemagglutinin repeat
906 965 InterPro IPR008619 Filamentous haemagglutinin repeat
1619 1678 Pfam PF05594 Haemagglutinin repeat
1619 1678 InterPro IPR008619 Filamentous haemagglutinin repeat
2485 2531 Pfam PF05594 Haemagglutinin repeat
2485 2531 InterPro IPR008619 Filamentous haemagglutinin repeat
589 644 Pfam PF05594 Haemagglutinin repeat
589 644 InterPro IPR008619 Filamentous haemagglutinin repeat
1910 1982 Pfam PF05594 Haemagglutinin repeat
1910 1982 InterPro IPR008619 Filamentous haemagglutinin repeat
1133 1200 Pfam PF05594 Haemagglutinin repeat
1133 1200 InterPro IPR008619 Filamentous haemagglutinin repeat
2158 2185 Pfam PF05594 Haemagglutinin repeat
2158 2185 InterPro IPR008619 Filamentous haemagglutinin repeat
823 886 Pfam PF05594 Haemagglutinin repeat
823 886 InterPro IPR008619 Filamentous haemagglutinin repeat
980 1054 Pfam PF05594 Haemagglutinin repeat
980 1054 InterPro IPR008619 Filamentous haemagglutinin repeat
2575 2614 Pfam PF05594 Haemagglutinin repeat
2575 2614 InterPro IPR008619 Filamentous haemagglutinin repeat
27 3535 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
10 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
36 327 Gene3D G3DSA:2.160.20.10 -
36 327 InterPro IPR012334 Pectin lyase fold
47 168 SMART SM00912 Haemagg_act_2a
47 168 InterPro IPR008638 Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain
1 28 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
2626 2692 Pfam PF13332 Hemagglutinin repeat
2626 2692 InterPro IPR025157 Hemagglutinin repeat
2696 2836 Pfam PF13332 Hemagglutinin repeat
2696 2836 InterPro IPR025157 Hemagglutinin repeat
1 28 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
585 625 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
585 625 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
462 501 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
462 501 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1413 1443 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1413 1443 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
2580 2611 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
2580 2611 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1066 1106 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1066 1106 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1219 1252 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1219 1252 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
419 460 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
419 460 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1581 1613 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1581 1613 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1447 1484 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1447 1484 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1530 1571 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1530 1571 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1254 1294 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1254 1294 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
812 852 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
812 852 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1045 1084 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1045 1084 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
729 769 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
729 769 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1088 1126 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1088 1126 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1003 1042 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1003 1042 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1149 1185 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1149 1185 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1867 1903 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1867 1903 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
937 969 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
937 969 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1108 1148 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1108 1148 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1340 1380 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1340 1380 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
688 727 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
688 727 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1296 1337 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1296 1337 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
542 582 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
542 582 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1905 1942 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1905 1942 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
311 350 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
311 350 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
2044 2083 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
2044 2083 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1190 1220 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1190 1220 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
2511 2547 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
2511 2547 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1662 1700 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1662 1700 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
853 892 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
853 892 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
770 809 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
770 809 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
505 540 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
505 540 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1423 1464 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1423 1464 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
958 1001 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
958 1001 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1382 1421 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1382 1421 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
606 644 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
606 644 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1486 1529 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
1486 1529 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
379 418 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
379 418 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
895 935 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
895 935 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
2492 2531 NCBIfam TIGR01731 filamentous hemagglutinin 20-residue repeat (two copies)
2492 2531 InterPro IPR010069 Toxin CdiA-like, Filamentous hemagglutinin motif repeats
1 27 SignalP_EUK SignalP-noTM SignalP-noTM
22 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
3401 3531 Gene3D G3DSA:3.40.1350.120 -
2969 3136 Pfam PF04830 Possible hemagglutinin (DUF637)
2969 3136 InterPro IPR006915 Domain of unknown function DUF637, haemagglutinin putative
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
3447 3524 Pfam PF18451 Contact-dependent growth inhibition CdiA C-terminal domain
3447 3524 InterPro IPR040559 tRNA nuclease CdiA, C-terminal
45 318 SUPERFAMILY SSF51126 Pectin lyase-like
45 318 InterPro IPR011050 Pectin lyase fold/virulence factor

3D Structure

No structural model is available for this protein.

Structure unavailable

No pre-computed model was found in the AlphaFold database and no ColabFold prediction is available for this protein.

Sequence length: 3535 aa