Protein profile

PA0081

Fha domain-containing protein

Genome: NC_002516.2

Gene: fha1 PA0081 Structure source: AlphaFold UniProt Q9I751
Export view
Amino acids 497
Annotations 1
Features 18
PDB binders 0
Druggability 0.525

Overview

Basic information about this protein and its source genome.

Accession
PA0081
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
fha1 PA0081
Status
annotated
Amino acids
497
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.525
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
3 491 NCBIfam TIGR03354 type VI secretion system-associated FHA domain protein TagH
3 491 InterPro IPR017735 Type VI secretion system, FHA domain-containing protein
27 78 SMART SM00240 FHA_2
27 78 InterPro IPR000253 Forkhead-associated (FHA) domain
262 290 MobiDBLite mobidb-lite consensus disorder prediction
13 107 SUPERFAMILY SSF49879 SMAD/FHA domain
13 107 InterPro IPR008984 SMAD/FHA domain superfamily
4 104 CDD cd00060 FHA
29 97 Pfam PF00498 FHA domain
29 97 InterPro IPR000253 Forkhead-associated (FHA) domain
311 489 Pfam PF20232 C-terminal domain of Type VI secretion system FHA protein
311 489 InterPro IPR046883 Type VI secretion system, FHA domain-containing protein, C-terminal domain
28 73 ProSiteProfiles PS50006 Forkhead-associated (FHA) domain profile.
28 73 InterPro IPR000253 Forkhead-associated (FHA) domain
137 301 MobiDBLite mobidb-lite consensus disorder prediction
238 252 MobiDBLite mobidb-lite consensus disorder prediction
193 217 MobiDBLite mobidb-lite consensus disorder prediction
5 108 Gene3D G3DSA:2.60.200.20 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0081
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.525
10 0.406
5 0.303