Protein profile

PA0082

hypothetical protein

Genome: NC_002516.2

Gene: tssA1 PA0082 Structure source: AlphaFold UniProt Q9I750

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Amino acids 344

Annotations 1

Features 6

PDB binders 0

Druggability 0.95

Overview

Basic information about this protein and its source genome.

Accession: PA0082
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: tssA1 PA0082
Status: annotated
Amino acids: 344
Structure source: AlphaFold

GO:0033104 A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.95

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0033104 A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records

Show feature table

Start	End	DB	Term	Name
1	343	PANTHER	PTHR37951	CYTOPLASMIC PROTEIN-RELATED
1	343	InterPro	IPR017740	Type VI secretion system protein TssA-like
3	340	NCBIfam	TIGR03363	type VI secretion system protein TssA
3	340	InterPro	IPR017740	Type VI secretion system protein TssA-like
8	131	Pfam	PF06812	ImpA, N-terminal, type VI secretion system
8	131	InterPro	IPR010657	ImpA, N-terminal

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0082	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
6				0.927
4				0.235