Overview
Basic information about this protein and its source genome.
- Accession
- PA0083
- Gene
- PA0083 tssB1
- Status
- annotated
- Amino acids
- 172
- Structure source
- Experimental + AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 12 | 162 | Pfam | PF05591 | Type VI secretion system, VipA, VC_A0107 or Hcp2 |
| 12 | 162 | InterPro | IPR008312 | Type VI secretion system sheath protein TssB1 |
| 171 | 172 | Coils | Coil | Coil |
| 8 | 163 | NCBIfam | TIGR03358 | type VI secretion system contractile sheath small subunit |
| 8 | 163 | InterPro | IPR008312 | Type VI secretion system sheath protein TssB1 |
| 3 | 172 | PIRSF | PIRSF028301 | UCP028301 |
| 3 | 172 | InterPro | IPR008312 | Type VI secretion system sheath protein TssB1 |
| 4 | 169 | PANTHER | PTHR35850 | CYTOPLASMIC PROTEIN-RELATED |
| 4 | 169 | InterPro | IPR008312 | Type VI secretion system sheath protein TssB1 |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
2 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 3 | 0.878 | ||||||
| 2 | 0.482 | ||||||
| 4 | 0.352 | ||||||
| 5 | 0.295 |