Protein profile

PA0084

hypothetical protein

Genome: NC_002516.2

Gene: PA0084 tssC1 Structure source: AlphaFold UniProt Q9I748

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Amino acids 498

Annotations 0

Features 8

PDB binders 0

Druggability 0.806

Overview

Basic information about this protein and its source genome.

Accession: PA0084
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0084 tssC1
Status: annotated
Amino acids: 498
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.806

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
381	492	Pfam	PF18945	EvpB/VC_A0108, tail sheath gpW/gp25-like domain
381	492	InterPro	IPR044032	TssC1, C-terminal
19	493	NCBIfam	TIGR03355	type VI secretion system contractile sheath large subunit
19	493	InterPro	IPR010269	Type VI secretion system TssC-like
6	497	PANTHER	PTHR35565	CYTOPLASMIC PROTEIN-RELATED
6	497	InterPro	IPR010269	Type VI secretion system TssC-like
69	371	Pfam	PF05943	EvpB/VC_A0108, tail sheath N-terminal domain
69	371	InterPro	IPR044031	TssC1, N-terminal

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0084	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.806
2				0.596
3				0.476