Protein profile

PA0086

hypothetical protein

Genome: NC_002516.2

Gene: PA0086 tagJ Structure source: Experimental + AlphaFold UniProt Q9I746
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Amino acids 281
Annotations 1
Features 9
PDB binders 0
Druggability 0.915

Overview

Basic information about this protein and its source genome.

Accession
PA0086
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0086 tagJ
Status
annotated
Amino acids
281
Structure source
Experimental + AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.915
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
22 42 Coils Coil Coil
26 82 Pfam PF14559 Tetratricopeptide repeat
159 274 Pfam PF07024 ImpE protein
159 274 InterPro IPR009211 Type VI secretion system accessory component TagJ
4 281 PIRSF PIRSF029288 SciE_ImpE
4 281 InterPro IPR009211 Type VI secretion system accessory component TagJ
18 106 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
18 106 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
23 278 SUPERFAMILY SSF144059 ImpE-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

3 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4UQX
X-ray 1.20 Å A
92.9% 21-281
PDBe RCSB PDBj File
Viewing
PDB 4UQY
X-ray 1.60 Å A
92.9% 21-281
PDBe RCSB PDBj File
Loaded
PDB 4UQZ
X-ray 1.60 Å A
92.9% 21-281
PDBe RCSB PDBj File
Loaded
AlphaFold PA0086
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.696
1 0.525

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.58 0.074
2 1.91 0.039
3 1.91 0.039