Protein profile

PA0107

cytochrome C oxidase assembly protein

Genome: NC_002516.2

Gene: PA0107 Structure source: AlphaFold UniProt Q9I725
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Amino acids 184
Annotations 2
Features 13
PDB binders 0
Druggability 0.793

Overview

Basic information about this protein and its source genome.

Accession
PA0107
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0107
Status
annotated
Amino acids
184
Structure source
AlphaFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0005507 Binding to a copper (Cu) ion.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
34.536
Human E-value
3.43e-28
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.793
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
  • GO:0005507 Binding to a copper (Cu) ion.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
12 33 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
5 171 PANTHER PTHR21320 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED
54 174 SUPERFAMILY SSF110111 Ctag/Cox11
54 174 InterPro IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily
13 35 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 182 PIRSF PIRSF005413 COX11
1 182 InterPro IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11
34 184 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
29 171 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11
29 171 InterPro IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11
1 11 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
53 182 Gene3D G3DSA:2.60.370.10 Ctag/Cox11
53 182 InterPro IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0107
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.238