Protein profile

PA0125

hypothetical protein

Genome: NC_002516.2

Gene: PA0125 Structure source: Experimental + AlphaFold UniProt Q9I707
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Amino acids 75
Annotations 1
Features 6
PDB binders 0
Druggability 0.961

Overview

Basic information about this protein and its source genome.

Accession
PA0125
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0125
Status
annotated
Amino acids
75
Structure source
Experimental + AlphaFold
GO
GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.961
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
3 46 CDD cd22233 RHH_CopAso-like
16 72 SUPERFAMILY SSF48092 Transcription factor STAT-4 N-domain
16 72 InterPro IPR036535 STAT transcription factor, N-terminal domain superfamily
2 73 PANTHER PTHR40688 -
5 42 Pfam PF01402 Ribbon-helix-helix protein, copG family
5 42 InterPro IPR002145 Ribbon-helix-helix protein, CopG

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 6XRW
X-ray 1.77 Å B,D
100.0% 1-75
PDBe RCSB PDBj File
Viewing
AlphaFold PA0125
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.961
2 0.25