Protein profile

PA0127

hypothetical protein

Genome: NC_002516.2

Gene: PA0127 Structure source: AlphaFold UniProt Q9I705
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Amino acids 166
Annotations 1
Features 13
PDB binders 0
Druggability 0.949

Overview

Basic information about this protein and its source genome.

Accession
PA0127
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0127
Status
annotated
Amino acids
166
Structure source
AlphaFold
GO
GO:0009269 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.949
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0009269 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
10 20 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 27 Phobius SIGNAL_PEPTIDE Signal peptide region
1 23 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
34 154 SMART SM00769 why
34 154 InterPro IPR013990 Water stress and hypersensitive response domain
28 166 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
12 153 SUPERFAMILY SSF117070 LEA14-like
30 155 Gene3D G3DSA:2.60.40.1820 -
1 27 SignalP_EUK SignalP-noTM SignalP-noTM
21 27 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
54 147 Pfam PF03168 Late embryogenesis abundant protein
54 147 InterPro IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0127
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.949