Protein profile

PA0131

beta-alanine degradation protein BauB

Genome: NC_002516.2

Gene: bauB PA0131 Structure source: AlphaFold UniProt Q9I701

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Amino acids 95

Annotations 1

Features 8

PDB binders 0

Druggability 0.879

Overview

Basic information about this protein and its source genome.

Accession: PA0131
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: bauB PA0131
Status: annotated
Amino acids: 95
Structure source: AlphaFold

GO:0019483 The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.879

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0019483 The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
6	95	CDD	cd06982	cupin_BauB-like
2	95	FunFam	G3DSA:2.60.120.10:FF:000168	Cupin domain-containing protein
23	90	Pfam	PF07883	Cupin domain
23	90	InterPro	IPR013096	Cupin 2, conserved barrel
4	91	SUPERFAMILY	SSF51182	RmlC-like cupins
4	91	InterPro	IPR011051	RmlC-like cupin domain superfamily
2	95	Gene3D	G3DSA:2.60.120.10	Jelly Rolls
2	95	InterPro	IPR014710	RmlC-like jelly roll fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0131	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.879