Protein profile

PA0186

ABC transporter

Genome: NC_002516.2

Gene: IPC1295_25665 CAZ10_16140 ssuA_1 PA0186 atsR PAERUG_P19_London_7_VIM_2_05_10_00372 GUL26_28400 Structure source: AlphaFold UniProt O33416 UniProt G3XD96
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Amino acids 353
Annotations 0
Features 16
PDB binders 0
Druggability 0.91

Overview

Basic information about this protein and its source genome.

Accession
PA0186
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
IPC1295_25665 CAZ10_16140 ssuA_1 PA0186 atsR PAERUG_P19_London_7_VIM_2_05_10_00372 GUL26_28400
Status
annotated
Amino acids
353
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.91
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
36 341 Gene3D G3DSA:3.40.190.10 -
16 329 PANTHER PTHR30024 ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED
32 274 SUPERFAMILY SSF53850 Periplasmic binding protein-like II
1 30 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 18 SignalP_GRAM_NEGATIVE SignalP-TM SignalP-TM
3 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
31 353 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
22 30 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 30 Phobius SIGNAL_PEPTIDE Signal peptide region
126 227 FunFam G3DSA:3.40.190.10:FF:000282 Nitrate ABC transporter substrate-binding protein
68 260 Pfam PF09084 NMT1/THI5 like
68 260 InterPro IPR015168 SsuA/THI5-like
126 227 Gene3D G3DSA:3.40.190.10 -
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0186
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.91