Protein profile

PA0260

hypothetical protein

Genome: NC_002516.2

Gene: PA0260 tle3 Structure source: AlphaFold UniProt Q9I6M9

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Amino acids 716

Annotations 2

Features 7

PDB binders 0

Druggability 0.632

Overview

Basic information about this protein and its source genome.

Accession: PA0260
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0260 tle3
Status: annotated
Amino acids: 716
Structure source: AlphaFold

GO:0005576 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. GO:0044229 The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.632

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0005576 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
GO:0044229 The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
386	685	Pfam	PF11678	Protein of unknown function (DUF3274)
386	685	InterPro	IPR021692	Protein of unknown function DUF3274
138	310	Gene3D	G3DSA:3.40.50.1820	alpha/beta hydrolase
138	310	InterPro	IPR029058	Alpha/Beta hydrolase fold
68	87	MobiDBLite	mobidb-lite	consensus disorder prediction
181	278	SUPERFAMILY	SSF53474	alpha/beta-Hydrolases
181	278	InterPro	IPR029058	Alpha/Beta hydrolase fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0260	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
12				0.5
1				0.384