Protein profile

PA0271

hypothetical protein

Genome: NC_002516.2

Gene: PA0271 Structure source: AlphaFold UniProt Q9I6L9

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Amino acids 94

Annotations 2

Features 7

PDB binders 0

Druggability 0.807

Overview

Basic information about this protein and its source genome.

Accession: PA0271
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0271
Status: annotated
Amino acids: 94
Structure source: AlphaFold

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.807

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
5	68	Pfam	PF03992	Antibiotic biosynthesis monooxygenase
5	68	InterPro	IPR007138	Antibiotic biosynthesis monooxygenase domain
3	91	Gene3D	G3DSA:3.30.70.100	-
3	90	PANTHER	PTHR33336	QUINOL MONOOXYGENASE YGIN-RELATED
3	91	FunFam	G3DSA:3.30.70.100:FF:000055	Antibiotic biosynthesis monooxygenase
6	81	SUPERFAMILY	SSF54909	Dimeric alpha+beta barrel
6	81	InterPro	IPR011008	Dimeric alpha-beta barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0271	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.807