Protein profile

PA0360

hypothetical protein

Genome: NC_002516.2

Gene: PA0360 Structure source: AlphaFold UniProt Q9I6D4
Amino acids 328
Annotations 1
Features 34
PDB binders 0
Druggability 0.761

Overview

Basic information about this protein and its source genome.

Accession
PA0360
Gene
PA0360
Status
annotated
Amino acids
328
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
32.031
Human E-value
7.69e-09
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.761
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

MFSQWVFLSVLALAVPSFAWAEDAVSDLAREQSKAEQGDKRGDELFAEFTRLRQAAETGEPQALFDFGAYFYQQQNYASAREWWGKAAAAGMVRAQIQLAMLYRDGDGGPQDKTEAARWFRKAAEQGDAAAQNEMGVLYWRGEGVDQDRVKAGTWFERAAASGSEDAETNLGWFYLDDSQGVYSATSDEEAALLDRYAGSREKAFQWFCKAATQGDARAQFKVGEAYWNGSGAGMNKLQARLWLEKAAQQQDADAIAWLESAANAAWYTRLENWIHAALDGELSGVADCSGAADRRHSGRGMEGAPSDPEAVEASAEDAQQAVEAASQ

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

34 records
Show feature table
Start End DB Term Name
61 92 SMART SM00671 sel1
61 92 InterPro IPR006597 Sel1-like repeat
165 216 SMART SM00671 sel1
165 216 InterPro IPR006597 Sel1-like repeat
93 128 SMART SM00671 sel1
93 128 InterPro IPR006597 Sel1-like repeat
217 252 SMART SM00671 sel1
217 252 InterPro IPR006597 Sel1-like repeat
129 164 SMART SM00671 sel1
129 164 InterPro IPR006597 Sel1-like repeat
1 21 SignalP_EUK SignalP-noTM SignalP-noTM
52 177 SUPERFAMILY SSF81901 HCP-like
17 193 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
17 193 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
194 275 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
194 275 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
5 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
16 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
290 328 MobiDBLite mobidb-lite consensus disorder prediction
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
52 167 PANTHER PTHR43628 ACTIVATOR OF C KINASE PROTEIN 1-RELATED
67 91 Pfam PF08238 Sel1 repeat
67 91 InterPro IPR006597 Sel1-like repeat
94 128 Pfam PF08238 Sel1 repeat
94 128 InterPro IPR006597 Sel1-like repeat
217 251 Pfam PF08238 Sel1 repeat
217 251 InterPro IPR006597 Sel1-like repeat
129 164 Pfam PF08238 Sel1 repeat
201 216 Pfam PF08238 Sel1 repeat
201 216 InterPro IPR006597 Sel1-like repeat
22 328 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
196 259 SUPERFAMILY SSF81901 HCP-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0360
AlphaFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.761