Protein profile

PA0388

hypothetical protein

Genome: NC_002516.2

Gene: PA0388 Structure source: Experimental + AlphaFold UniProt Q9I6A7
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Amino acids 139
Annotations 0
Features 10
PDB binders 0
Druggability 0.919

Overview

Basic information about this protein and its source genome.

Accession
PA0388
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0388
Status
annotated
Amino acids
139
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.919
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
16 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
23 138 Pfam PF14467 Domain of unknown function (DUF4426)
23 138 InterPro IPR025218 Domain of unknown function DUF4426
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
14 139 Gene3D G3DSA:2.60.40.3340 Domain of unknown function DUF4426
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
20 139 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 3UC2
X-ray 2.09 Å A,B,C,D
86.3% 20-139
PDBe RCSB PDBj File
Viewing
AlphaFold PA0388
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.919

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.53 0.071