Protein profile

PA0389

hypothetical protein

Genome: NC_002516.2

Gene: PA0389 Structure source: AlphaFold UniProt Q9I6A6
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Amino acids 206
Annotations 1
Features 9
PDB binders 0
Druggability 0.584

Overview

Basic information about this protein and its source genome.

Accession
PA0389
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0389
Status
annotated
Amino acids
206
Structure source
AlphaFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.584
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
2 194 Pfam PF07021 Methionine biosynthesis protein MetW
2 194 InterPro IPR010743 Methionine biosynthesis MetW
2 194 NCBIfam TIGR02081 methionine biosynthesis protein MetW
17 105 CDD cd02440 AdoMet_MTases
4 181 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39
4 181 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
12 139 PANTHER PTHR42912 METHYLTRANSFERASE
3 192 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
3 192 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0389
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.584