Protein profile

PA0484

hypothetical protein

Genome: NC_002516.2

Gene: PA0484 Structure source: AlphaFold UniProt Q9I634
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Amino acids 171
Annotations 3
Features 16
PDB binders 0
Druggability 0.894

Overview

Basic information about this protein and its source genome.

Accession
PA0484
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0484
Status
annotated
Amino acids
171
Structure source
AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0006351 The synthesis of an RNA transcript from a DNA template. GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.894
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0006351 The synthesis of an RNA transcript from a DNA template.
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 77 Gene3D G3DSA:3.30.70.260 -
90 169 CDD cd04869 ACT_GcvR_2
87 168 SUPERFAMILY SSF55021 ACT-like
87 168 InterPro IPR045865 ACT-like domain
84 169 Gene3D G3DSA:3.30.70.260 -
2 168 PANTHER PTHR34875 UPF0237 PROTEIN MJ1558
1 171 PIRSF PIRSF028103 GcvR
1 171 InterPro IPR016867 Glycine cleavage system transcriptional repressor
1 67 SUPERFAMILY SSF55021 ACT-like
1 67 InterPro IPR045865 ACT-like domain
96 125 Pfam PF01842 ACT domain
96 125 InterPro IPR002912 ACT domain
90 169 ProSiteProfiles PS51671 ACT domain profile.
90 169 InterPro IPR002912 ACT domain
3 65 Pfam PF13740 ACT domain
84 169 FunFam G3DSA:3.30.70.260:FF:000084 ACT domain-containing protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0484
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.894
1 0.767