Overview
Basic information about this protein and its source genome.
- Accession
- PA0525
- Gene
- PA0525
- Status
- annotated
- Amino acids
- 612
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
Gene Ontology (GO)
1- GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 421 | 604 | SMART | SM00327 | VWA_4 |
| 421 | 604 | InterPro | IPR002035 | von Willebrand factor, type A |
| 421 | 610 | ProSiteProfiles | PS50234 | VWFA domain profile. |
| 421 | 610 | InterPro | IPR002035 | von Willebrand factor, type A |
| 72 | 611 | PANTHER | PTHR41248 | NORD PROTEIN |
| 431 | 593 | CDD | cd01454 | vWA_norD_type |
| 422 | 601 | Gene3D | G3DSA:3.40.50.410 | von Willebrand factor, type A domain |
| 422 | 601 | InterPro | IPR036465 | von Willebrand factor A-like domain superfamily |
| 424 | 608 | SUPERFAMILY | SSF53300 | vWA-like |
| 424 | 608 | InterPro | IPR036465 | von Willebrand factor A-like domain superfamily |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA0525
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 2 | 0.861 | ||||||
| 14 | 0.37 |