Protein profile

PA0536

hypothetical protein

Genome: NC_002516.2

Gene: PA0536 Structure source: AlphaFold UniProt Q9I600
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Amino acids 341
Annotations 0
Features 21
PDB binders 0
Druggability 0.95

Overview

Basic information about this protein and its source genome.

Accession
PA0536
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0536
Status
annotated
Amino acids
341
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.95
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

21 records
Show feature table
Start End DB Term Name
218 238 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
167 202 MobiDBLite mobidb-lite consensus disorder prediction
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
239 249 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
289 308 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
287 309 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
270 288 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
250 269 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
31 154 Pfam PF04536 TPM domain
31 154 InterPro IPR007621 TPM domain
16 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
250 272 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
18 165 Gene3D G3DSA:3.10.310.50 -
309 341 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
20 217 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
16 341 PANTHER PTHR30373 UNCHARACTERIZED
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
215 237 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0536
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.95