Protein profile

PA0544

hypothetical protein

Genome: NC_002516.2

Gene: PA0544 Structure source: AlphaFold UniProt Q9I5Z2

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Amino acids 247

Annotations 1

Features 9

PDB binders 0

Druggability 0.676

Overview

Basic information about this protein and its source genome.

Accession: PA0544
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0544
Status: annotated
Amino acids: 247
Structure source: AlphaFold

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.676

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MKIRLLSDLHHEHFDGRRQLPEVEADVVVLAGDIHSHLEGLHWARETFADSEIVYVAGNHEFYSSEMTDLTQAMRNIARALEIHFLENDEARIGPARFLGATLWTDFQLYGADGYAPAHELALQSMPDFSCIDWFGGDFTPEQSIALHQASRDWLAEQLARPHDGPTLVVSHHAPSALSIPPQFVGNPLSPAFASNLDELVAQADYWLHGHVHDALDYRIGRARVLANPGGYPHERGGFRPEFVFEV

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records

Show feature table

Start	End	DB	Term	Name
1	97	Gene3D	G3DSA:3.60.21.10	-
1	97	InterPro	IPR029052	Metallo-dependent phosphatase-like
136	240	Gene3D	G3DSA:3.60.21.10	-
136	240	InterPro	IPR029052	Metallo-dependent phosphatase-like
1	214	Pfam	PF00149	Calcineurin-like phosphoesterase
1	214	InterPro	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
1	231	SUPERFAMILY	SSF56300	Metallo-dependent phosphatases
1	231	InterPro	IPR029052	Metallo-dependent phosphatase-like
2	238	PANTHER	PTHR37844	SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0544	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.676