Protein profile

PA0565

hypothetical protein

Genome: NC_002516.2

Gene: PA0565 Structure source: Experimental + AlphaFold UniProt Q9I5X1
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Amino acids 112
Annotations 2
Features 9
PDB binders 0
Druggability 0.805

Overview

Basic information about this protein and its source genome.

Accession
PA0565
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0565
Status
annotated
Amino acids
112
Structure source
Experimental + AlphaFold
GO
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0051920 Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.805
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
  • GO:0051920 Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 112 Gene3D G3DSA:1.20.1290.10 -
1 112 InterPro IPR029032 AhpD-like
5 111 SUPERFAMILY SSF69118 AhpD-like
5 111 InterPro IPR029032 AhpD-like
24 106 Pfam PF02627 Carboxymuconolactone decarboxylase family
24 106 InterPro IPR003779 Carboxymuconolactone decarboxylase-like
1 110 PANTHER PTHR33930 ALKYL HYDROPEROXIDE REDUCTASE AHPD
40 90 NCBIfam TIGR00778 alkylhydroperoxidase AhpD family core domain
40 90 InterPro IPR004675 Alkylhydroperoxidase AhpD core

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 7Y4R
X-ray 2.51 Å A,B,C,D,E,F
100.0% 1-112
PDBe RCSB PDBj File
Viewing
AlphaFold PA0565
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.805

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.68 0.204
2 1.35 0.016