Overview
Basic information about this protein and its source genome.
- Accession
- PA0598
- Gene
- PA0598
- Status
- annotated
- Amino acids
- 252
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- CytoplasmicMembrane
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 190 | 245 | Pfam | PF00226 | DnaJ domain |
| 190 | 245 | InterPro | IPR001623 | DnaJ domain |
| 190 | 242 | CDD | cd06257 | DnaJ |
| 190 | 242 | InterPro | IPR001623 | DnaJ domain |
| 33 | 252 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. |
| 7 | 29 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 230 | 250 | PRINTS | PR00625 | DnaJ domain signature |
| 230 | 250 | InterPro | IPR001623 | DnaJ domain |
| 206 | 221 | PRINTS | PR00625 | DnaJ domain signature |
| 206 | 221 | InterPro | IPR001623 | DnaJ domain |
| 188 | 206 | PRINTS | PR00625 | DnaJ domain signature |
| 188 | 206 | InterPro | IPR001623 | DnaJ domain |
| 190 | 246 | PANTHER | PTHR24074 | CO-CHAPERONE PROTEIN DJLA |
| 130 | 244 | SUPERFAMILY | SSF46565 | Chaperone J-domain |
| 130 | 244 | InterPro | IPR036869 | Chaperone J-domain superfamily |
| 12 | 32 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 59 | 158 | CDD | cd07316 | terB_like_DjlA |
| 177 | 250 | Gene3D | G3DSA:1.10.287.110 | DnaJ domain |
| 177 | 250 | InterPro | IPR036869 | Chaperone J-domain superfamily |
| 186 | 252 | ProSiteProfiles | PS50076 | dnaJ domain profile. |
| 186 | 252 | InterPro | IPR001623 | DnaJ domain |
| 110 | 130 | Coils | Coil | Coil |
| 50 | 176 | Gene3D | G3DSA:1.10.3680.10 | - |
| 50 | 176 | InterPro | IPR029024 | TerB-like |
| 185 | 250 | SMART | SM00271 | dnaj_3 |
| 185 | 250 | InterPro | IPR001623 | DnaJ domain |
| 1 | 11 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 21 | 175 | SUPERFAMILY | SSF158682 | TerB-like |
| 21 | 175 | InterPro | IPR029024 | TerB-like |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA0598
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 6 | 0.356 | ||||||
| 4 | 0.302 |