Protein profile

PA0616

hypothetical protein

Genome: NC_002516.2

Gene: PA0616 GUL26_17440 VR2 PAERUG_P19_London_7_VIM_2_05_10_01890 L4V69_06730 Structure source: Experimental + AlphaFold UniProt Q9S581 UniProt G3XCT9
Amino acids 185
Annotations 0
Features 10
PDB binders 0
Druggability 0.881

Overview

Basic information about this protein and its source genome.

Accession
PA0616
Gene
PA0616 GUL26_17440 VR2 PAERUG_P19_London_7_VIM_2_05_10_01890 L4V69_06730
Status
annotated
Amino acids
185
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.881
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
4 87 Gene3D G3DSA:2.40.50.230 -
4 87 InterPro IPR037026 Vgr protein, OB-fold domain superfamily
8 185 NCBIfam TIGR01644 phage baseplate assembly protein V
8 185 InterPro IPR013046 Phage baseplate assembly protein V/Gp45
90 167 Gene3D G3DSA:6.20.150.10 -
12 29 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
30 185 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 11 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
18 84 Pfam PF04717 Type VI secretion system/phage-baseplate injector OB domain
18 84 InterPro IPR006531 Gp5/Type VI secretion system Vgr protein, OB-fold domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

2 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4S37
X-ray 2.20 Å A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R
100.0% 1-185
Viewing
PDB 4S36
X-ray 1.46 Å A
48.6% 96-185
Loaded
AlphaFold PA0616
AlphaFold full sequence Loaded
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