Overview
Basic information about this protein and its source genome.
- Accession
- PA0620
- Gene
- HR2 PA0620
- Status
- annotated
- Amino acids
- 691
- Structure source
- Experimental + AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Extracellular
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
Gene Ontology (GO)
1- GO:0046872 Binding to a metal ion.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 7 | 158 | Pfam | PF12571 | Phage tail-collar fibre protein |
| 7 | 158 | InterPro | IPR022225 | Phage tail fibre protein |
| 1 | 690 | PANTHER | PTHR35191 | PROPHAGE SIDE TAIL FIBER PROTEIN HOMOLOG STFQ-RELATED |
| 360 | 440 | CDD | cd19958 | pyocin_knob |
| 600 | 690 | Gene3D | G3DSA:2.60.40.3940 | - |
| 451 | 529 | CDD | cd19958 | pyocin_knob |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
3 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
PDB
6CL6
|
X-ray | 1.90 Å | A,B,C,D,E,F |
|
Viewing | |
|
PDB
6CU2
|
X-ray | 2.58 Å | A |
|
Loaded | |
|
PDB
6CT8
|
X-ray | 2.62 Å | A |
|
Loaded | |
|
AlphaFold
PA0620
|
AlphaFold | — | — | full sequence | — | Loaded |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 2 | 0.846 | ||||||
| 1 | 0.419 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 1.38 | 0.017 |
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 2 | 0.871 | ||||||
| 1 | 0.407 | ||||||
| 4 | 0.223 |