Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA0641
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0641
Status: annotated
Amino acids: 1204
Structure source: AlphaFold

GO

GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.807

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MNKTITGHKGGSKKPRQPVEMPDSVRSIARAKILLALGEGEFDGGVDGRSIYLDDTPLLAADGSVNFPGVTWEFRPGSVDQEHIAGVPAVENELAVGVELKSDAPWVRAVNNTQLSAVRLRLSWPAIQRQQENGDVVGYRIDYAIDIAVDGGAWQEALKASLDDKSTSRYERSHRVDLPEARSGWQVRVRRLTPNQNNNRVADTMRVEAITEVIDAKLRYPNTALLFVEFDASQFQSIPQISVEARGRRVRVPSNYDPQTRSYSGTWDGSFKSAWTSNPAWHWYDIVLHKRFGLGRRIDASMVDKWSLYRIAQYCDQSVPDGKGGQEPRFSCNLYLQSRAEAWTVLRDLAAIFRGMSYWSGAEMVAVSDMPEDEAYTFSPSNTVRGDDGSHFNYSSSRQRDRHTLALVNYDNPGNGYQSQPVAVNNDRAQRRYGISQLEITAIGCTSEGEAQRRGQWALLTEELEQDAVTFRTGMDGRGLAPGKIIAVADPVKSGKQIGGRLSAVDGRALTLDRDVEARPGDRLLVNLPNGKAEARSVQSVVGRVLTVTAAYSETPRPQGQWALQSNSLTTQRFRIMSITRPEDNLFEITALQHNASKFDAIDNGARIELPPVTSIPPGVQAPPQNVRIKAFTKVDQGLAVTSLSASWDAAPNAVAYEAEWRKDSGNWVRVPRTSALGFDVPGIYAGRYLVRVRALNVMEVGSVYASSVETALEGKTTPPPALAYLRCVAGPWRIGLEWGFPTSGAADTAYTEIQQSATPGGSEETARALGLFAYPGNTHLVSPIPAGERLAFRGRLIDRSGNVGAWSNWVTGTSSSDASEYNQLITQEYVESALGQQFFSDIERMQVDIGGLQKQVGDLADVLLYDPAKVYAKNDMVRQGQRLYQALKAVPAKTAPPNAAYWSDIGQSLETANGLAQQVASHTAEISELDGSLTAQASRLGVLQAATRDDADDGNGAMADALRGWKTVARAAQEETVRATENEAQATRTTLLEARTADAEGRIATVERVATSDRQATAQRLDQLSASIGGTAASLQSEQTARANADSALAQRIDTVQARTDTNSAAIQTTSQAVTSLDGNVKAMYSVKLQAHANGQKYAAGWQLGFDSGTSVSTMAFQADRFIWFDSSSGTAVAPVSIVNGQMFIKNALIQDGAIDNAKIGNVIQSNAMSNNGMPIWRLDKAGTYTVRDSAGQVRVEMGLLQS

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

GO:0005515 Binding to a protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records

Show feature table

Start	End	DB	Term	Name
622	715	Gene3D	G3DSA:2.60.40.10	Immunoglobulins
622	715	InterPro	IPR013783	Immunoglobulin-like fold
339	503	Pfam	PF13550	Putative phage tail protein
339	503	InterPro	IPR032876	Tip attachment protein J
623	721	ProSiteProfiles	PS50853	Fibronectin type-III domain profile.
623	721	InterPro	IPR003961	Fibronectin type III
623	702	CDD	cd00063	FN3
623	702	InterPro	IPR003961	Fibronectin type III
1068	1146	Pfam	PF09327	Domain of unknown function (DUF1983)
1068	1146	InterPro	IPR015406	Domain of unknown function DUF1983
2	1195	PANTHER	PTHR36251	FELS-1 PROPHAGE HOST SPECIFICITY PROTEIN-RELATED
622	710	SUPERFAMILY	SSF49265	Fibronectin type III
622	710	InterPro	IPR036116	Fibronectin type III superfamily
1	22	MobiDBLite	mobidb-lite	consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0641	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.807

PA0641