Protein profile

PA0653

hypothetical protein

Genome: NC_002516.2

Gene: PA0653 Structure source: AlphaFold UniProt G3XDA4

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Amino acids 140

Annotations 0

Features 8

PDB binders 0

Druggability 0.857

Overview

Basic information about this protein and its source genome.

Accession: PA0653
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0653
Status: annotated
Amino acids: 140
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.857

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
39	139	Gene3D	G3DSA:3.30.300.20	-
39	139	InterPro	IPR015946	K homology domain-like, alpha/beta
34	132	Pfam	PF02566	OsmC-like protein
34	132	InterPro	IPR003718	OsmC/Ohr family
1	137	SUPERFAMILY	SSF82784	OsmC-like
1	137	InterPro	IPR036102	OsmC/Ohr superfamily
1	137	PANTHER	PTHR34352	PROTEIN YHFA
1	33	Gene3D	G3DSA:2.20.25.10	-

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0653	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.857