Protein profile

PA0663

hypothetical protein

Genome: NC_002516.2

Gene: PA0663 Structure source: AlphaFold UniProt Q9I5Q8

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Amino acids 239

Annotations 0

Features 9

PDB binders 0

Druggability 0.378

Overview

Basic information about this protein and its source genome.

Accession: PA0663
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0663
Status: annotated
Amino acids: 239
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.378

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records

Show feature table

Start	End	DB	Term	Name
35	43	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
1	43	Phobius	SIGNAL_PEPTIDE	Signal peptide region
50	77	Coils	Coil	Coil
15	37	TMHMM	TMhelix	Region of a membrane-bound protein predicted to be embedded in the membrane.
44	239	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
19	34	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
1	18	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
67	219	Pfam	PF20567	Family of unknown function (DUF6776)
67	219	InterPro	IPR046703	Protein of unknown function DUF6776

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0663	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.378