Protein profile

PA0671

hypothetical protein

Genome: NC_002516.2

Gene: PA0671 Structure source: AlphaFold UniProt Q9I5Q0

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Amino acids 183

Annotations 1

Features 9

PDB binders 0

Druggability 0.93

Overview

Basic information about this protein and its source genome.

Accession: PA0671
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0671
Status: annotated
Amino acids: 183
Structure source: AlphaFold

GO:0006281 The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.93

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0006281 The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records

Show feature table

Start	End	DB	Term	Name
3	160	PANTHER	PTHR35369	BLR3025 PROTEIN-RELATED
5	169	NCBIfam	NF033429	translesion DNA synthesis-associated protein ImuA
5	169	InterPro	IPR047610	Translesion DNA synthesis-associated protein ImuA
25	138	Gene3D	G3DSA:3.40.50.300	-
25	138	InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
26	139	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases
26	139	InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
1	181	PIRSF	PIRSF037290	UCP037290
1	181	InterPro	IPR017166	Uncharacterised conserved protein UCP037290

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0671	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.93
5				0.234