Amino acids
4180
Annotations
3
Features
23
PDB binders
0
Overview
Basic information about this protein and its source genome.
- Accession
- PA0690
- Gene
- PA0690
- Status
- annotated
- Amino acids
- 4180
- Structure source
- Unavailable
GO
GO:0005576 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
GO:0098046 A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).
GO:0046819 The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Extracellular
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
3 GO
Gene Ontology (GO)
3- GO:0005576 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
- GO:0098046 A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).
- GO:0046819 The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.
Sequence Features
Domain/signature hits from InterPro and related databases.
23 records
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 3971 | 4080 | Pfam | PF12545 | Filamentous haemagglutinin family outer membrane protein |
| 3971 | 4080 | InterPro | IPR021026 | Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 |
| 1 | 38 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM |
| 1 | 22 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. |
| 132 | 248 | SMART | SM00912 | Haemagg_act_2a |
| 132 | 248 | InterPro | IPR008638 | Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain |
| 4134 | 4180 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 139 | 452 | Gene3D | G3DSA:2.160.20.10 | - |
| 139 | 452 | InterPro | IPR012334 | Pectin lyase fold |
| 39 | 4180 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 1 | 38 | Phobius | SIGNAL_PEPTIDE | Signal peptide region |
| 135 | 382 | Pfam | PF05860 | TPS secretion domain |
| 135 | 382 | InterPro | IPR008638 | Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain |
| 145 | 480 | SUPERFAMILY | SSF51126 | Pectin lyase-like |
| 145 | 480 | InterPro | IPR011050 | Pectin lyase fold/virulence factor |
| 1 | 38 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM |
| 34 | 38 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. |
| 58 | 77 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 23 | 33 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. |
| 41 | 4179 | PANTHER | PTHR12338 | AUTOTRANSPORTER |
| 75 | 102 | Coils | Coil | Coil |
| 169 | 245 | NCBIfam | TIGR01901 | filamentous hemagglutinin family N-terminal domain |
| 169 | 245 | InterPro | IPR008638 | Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like, TPS domain |
3D Structure
No structural model is available for this protein.
Structure unavailable
No pre-computed model was found in the AlphaFold database and no ColabFold prediction is available for this protein.