Protein profile

PA0695

hypothetical protein

Genome: NC_002516.2

Gene: PA0695 Structure source: AlphaFold UniProt Q9I5N1
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Amino acids 248
Annotations 1
Features 12
PDB binders 0
Druggability 0.757

Overview

Basic information about this protein and its source genome.

Accession
PA0695
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0695
Status
annotated
Amino acids
248
Structure source
AlphaFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.757
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MNMSADPKHTPEPKNAAPLSIDGRPANPTLRYLKWGLGALLLAGLAWLVWEWANDMSGVRREAPKVPAIIPLPPPPPPPPEKPPEPEQPVEEEKIVEPEPQPELEEVKPQEEAPPSPADDLADPMQMDGDAQSGSDAFNIGAGKGGGMAGSGGGRAGNASYSQYLAYAFQRLLRDNPELRNLAFRLQAEIWLSSSGDITRAELTRSSGDPETDQKVLAALRAAGRLEERPPASLTLPVRIALQGKRPG

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
51 248 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
149 238 Gene3D G3DSA:3.30.1150.10 -
32 50 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
67 84 MobiDBLite mobidb-lite consensus disorder prediction
85 113 MobiDBLite mobidb-lite consensus disorder prediction
189 238 NCBIfam TIGR01352 TonB family C-terminal domain
189 238 InterPro IPR006260 TonB/TolA, C-terminal
180 230 Pfam PF13103 TonB C terminal
1 31 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
71 239 SUPERFAMILY SSF74653 TolA/TonB C-terminal domain
67 140 MobiDBLite mobidb-lite consensus disorder prediction
1 22 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0695
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.757