Protein profile

PA0726

hypothetical protein

Genome: NC_002516.2

Gene: PA0726 Structure source: AlphaFold UniProt Q9I5K2

Export view

Amino acids 424

Annotations 0

Features 9

PDB binders 0

Druggability 0.307

Overview

Basic information about this protein and its source genome.

Accession: PA0726
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0726
Status: annotated
Amino acids: 424
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.307

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records

Show feature table

Start	End	DB	Term	Name
229	247	Phobius	TRANSMEMBRANE	Region of a membrane-bound protein predicted to be embedded in the membrane.
248	424	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
229	248	TMHMM	TMhelix	Region of a membrane-bound protein predicted to be embedded in the membrane.
1	211	Gene3D	G3DSA:3.40.50.300	-
1	211	InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
400	424	MobiDBLite	mobidb-lite	consensus disorder prediction
2	213	Pfam	PF05707	Zonular occludens toxin (Zot)
2	213	InterPro	IPR008900	Zona occludens toxin, N-terminal
1	228	Phobius	CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0726	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.307