Protein profile

PA0801

hypothetical protein

Genome: NC_002516.2

Gene: PA0801 Structure source: AlphaFold UniProt Q9I5D7
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Amino acids 506
Annotations 0
Features 31
PDB binders 0
Druggability 0.628

Overview

Basic information about this protein and its source genome.

Accession
PA0801
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0801
Status
annotated
Amino acids
506
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.628
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

31 records
Show feature table
Start End DB Term Name
154 179 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 449 PANTHER PTHR34219 IRON-REGULATED INNER MEMBRANE PROTEIN-RELATED
1 449 InterPro IPR005625 PepSY-associated TM protein
433 450 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
180 202 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
206 332 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
333 355 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
389 402 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
131 153 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
180 205 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
16 27 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
12 34 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
451 464 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
465 486 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 32 Phobius SIGNAL_PEPTIDE Signal peptide region
28 32 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
365 387 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
10 356 Pfam PF03929 PepSY-associated TM region
10 356 InterPro IPR005625 PepSY-associated TM protein
422 432 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 15 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
433 450 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
403 421 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
367 388 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
331 353 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
356 366 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
402 421 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
33 130 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
487 506 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
465 487 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
131 153 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0801
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.628
2 0.55