Protein profile

PA0850

hypothetical protein

Genome: NC_002516.2

Gene: PA0850 Structure source: AlphaFold UniProt Q9I591
Export view
Amino acids 139
Annotations 1
Features 15
PDB binders 0
Druggability 0.876

Overview

Basic information about this protein and its source genome.

Accession
PA0850
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0850
Status
annotated
Amino acids
139
Structure source
AlphaFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.876
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 43 Phobius SIGNAL_PEPTIDE Signal peptide region
139 139 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
7 25 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
11 136 SUPERFAMILY SSF161084 MAPEG domain-like
11 136 InterPro IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily
3 136 Gene3D G3DSA:1.20.120.550 -
3 136 InterPro IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily
44 111 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
112 138 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
6 136 Pfam PF01124 MAPEG family
6 136 InterPro IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
113 135 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
4 26 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
26 43 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0850
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.876
1 0.704