Protein profile

PA0857

morphogene protein BolA

Genome: NC_002516.2

Gene: PA0857 bolA Structure source: AlphaFold UniProt Q9I584

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Amino acids 101

Annotations 2

Features 8

PDB binders 0

Druggability 0.526

Overview

Basic information about this protein and its source genome.

Accession: PA0857
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA0857 bolA
Status: annotated
Amino acids: 101
Structure source: AlphaFold

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0006351 The synthesis of an RNA transcript from a DNA template.

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 37.864
Human E-value: 2.71e-14
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.526

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0006351 The synthesis of an RNA transcript from a DNA template.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
1	85	Gene3D	G3DSA:3.10.20.90	-
13	80	Pfam	PF01722	BolA-like protein
13	80	InterPro	IPR002634	BolA protein
4	99	PANTHER	PTHR46229	BOLA TRANSCRIPTION REGULATOR
1	94	PIRSF	PIRSF003113	BolA
1	94	InterPro	IPR002634	BolA protein
3	83	SUPERFAMILY	SSF82657	BolA-like
3	83	InterPro	IPR036065	BolA-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA0857	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.526