Protein profile

PA0891

hypothetical protein

Genome: NC_002516.2

Gene: PA0891 aotO PAERUG_P19_London_7_VIM_2_05_10_01033 Structure source: AlphaFold UniProt O50184 UniProt G3XCZ4
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Amino acids 370
Annotations 2
Features 6
PDB binders 0
Druggability 0.658

Overview

Basic information about this protein and its source genome.

Accession
PA0891
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0891 aotO PAERUG_P19_London_7_VIM_2_05_10_01033
Status
annotated
Amino acids
370
Structure source
AlphaFold
GO
GO:0016788 Catalysis of the hydrolysis of any ester bond. GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.658
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
2 284 Gene3D G3DSA:3.40.630.10 Zn peptidases
18 363 SUPERFAMILY SSF53187 Zn-dependent exopeptidases
6 269 CDD cd06250 M14_PaAOTO_like
2 365 PANTHER PTHR37326 BLL3975 PROTEIN
29 357 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family
29 357 InterPro IPR007036 Succinylglutamate desuccinylase/aspartoacylase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0891
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.658
2 0.641