Protein profile

PA0919

hypothetical protein

Genome: NC_002516.2

Gene: PA0919 Structure source: AlphaFold UniProt Q9I538
Export view
Amino acids 427
Annotations 2
Features 17
PDB binders 0
Druggability 0.626

Overview

Basic information about this protein and its source genome.

Accession
PA0919
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0919
Status
annotated
Amino acids
427
Structure source
AlphaFold
GO
GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0055091 Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.626
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
  • GO:0055091 Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
27 34 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 34 Phobius SIGNAL_PEPTIDE Signal peptide region
12 31 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 10 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 34 ProSiteProfiles PS51318 Twin arginine translocation (Tat) signal profile.
1 34 InterPro IPR006311 Twin-arginine translocation pathway, signal sequence
11 26 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
232 421 Pfam PF06057 Bacterial virulence protein (VirJ)
232 421 InterPro IPR010333 Bacterial virulence
1 34 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
3 426 PIRSF PIRSF029063 IV_sec_VirJ
3 426 InterPro IPR011225 Type IV secretory pathway, VirJ component
35 427 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
177 381 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
177 381 InterPro IPR029058 Alpha/Beta hydrolase fold
220 407 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
220 407 InterPro IPR029058 Alpha/Beta hydrolase fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0919
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.615