Protein profile

PA0987

hypothetical protein

Genome: NC_002516.2

Gene: PA0987 Structure source: AlphaFold UniProt Q9I4Y2
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Amino acids 280
Annotations 2
Features 12
PDB binders 0
Druggability 0.508

Overview

Basic information about this protein and its source genome.

Accession
PA0987
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0987
Status
annotated
Amino acids
280
Structure source
AlphaFold
GO
GO:0003676 Binding to a nucleic acid. GO:0015074 The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.508
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0003676 Binding to a nucleic acid.
  • GO:0015074 The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
188 253 Pfam PF13683 Integrase core domain
188 253 InterPro IPR001584 Integrase, catalytic core
3 256 NCBIfam NF033516 IS3 family transposase
98 261 SUPERFAMILY SSF53098 Ribonuclease H-like
98 261 InterPro IPR012337 Ribonuclease H-like superfamily
100 239 Gene3D G3DSA:3.30.420.10 -
100 239 InterPro IPR036397 Ribonuclease H superfamily
100 261 ProSiteProfiles PS50994 Integrase catalytic domain profile.
100 261 InterPro IPR001584 Integrase, catalytic core
36 88 Pfam PF13276 HTH-like domain
36 88 InterPro IPR025948 HTH-like domain
1 269 PANTHER PTHR47515 LOW CALCIUM RESPONSE LOCUS PROTEIN T

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0987
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.508