Protein profile

PA0988

hypothetical protein

Genome: NC_002516.2

Gene: PA0988 Structure source: AlphaFold UniProt Q9I4Y1
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Amino acids 134
Annotations 1
Features 6
PDB binders 0
Druggability 0.869

Overview

Basic information about this protein and its source genome.

Accession
PA0988
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA0988
Status
annotated
Amino acids
134
Structure source
AlphaFold
GO
GO:0047617 Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.869
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0047617 Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
20 105 Pfam PF03061 Thioesterase superfamily
20 105 InterPro IPR006683 Thioesterase domain
2 133 SUPERFAMILY SSF54637 Thioesterase/thiol ester dehydrase-isomerase
2 133 InterPro IPR029069 HotDog domain superfamily
7 116 CDD cd00586 4HBT
2 134 Gene3D G3DSA:3.10.129.10 Hotdog Thioesterase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA0988
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.869
1 0.413