Protein profile

PA1009

hypothetical protein

Genome: NC_002516.2

Gene: PA1009 Structure source: AlphaFold UniProt Q9I4W4
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Amino acids 185
Annotations 3
Features 11
PDB binders 0
Druggability 0.633

Overview

Basic information about this protein and its source genome.

Accession
PA1009
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1009
Status
annotated
Amino acids
185
Structure source
AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0006351 The synthesis of an RNA transcript from a DNA template. GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.633
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0006351 The synthesis of an RNA transcript from a DNA template.
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
99 179 CDD cd04869 ACT_GcvR_2
7 182 PIRSF PIRSF028103 GcvR
7 182 InterPro IPR016867 Glycine cleavage system transcriptional repressor
7 90 Gene3D G3DSA:3.30.70.260 -
96 184 Gene3D G3DSA:3.30.70.260 -
9 83 Pfam PF13740 ACT domain
7 87 SUPERFAMILY SSF55021 ACT-like
7 87 InterPro IPR045865 ACT-like domain
95 181 SUPERFAMILY SSF55021 ACT-like
95 181 InterPro IPR045865 ACT-like domain
4 183 PANTHER PTHR34875 UPF0237 PROTEIN MJ1558

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1009
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.633