Protein profile

PA1019a

thioesterase

Genome: NC_002516.2

Gene: YP_008719738.1 Structure source: ColabFold
Amino acids 135
Annotations 0
Features 8
PDB binders 0
Druggability 0.253

Overview

Basic information about this protein and its source genome.

Accession
PA1019a
Gene
YP_008719738.1
Status
annotated
Amino acids
135
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.253
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
9 134 Gene3D G3DSA:3.10.129.10 Hotdog Thioesterase
18 126 NCBIfam TIGR00369 hotdog fold thioesterase
18 126 InterPro IPR003736 Phenylacetic acid degradation-related domain
20 129 CDD cd03443 PaaI_thioesterase
11 130 SUPERFAMILY SSF54637 Thioesterase/thiol ester dehydrase-isomerase
11 130 InterPro IPR029069 HotDog domain superfamily
51 121 Pfam PF03061 Thioesterase superfamily
51 121 InterPro IPR006683 Thioesterase domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold PA1019A
ColabFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.253