Overview
Basic information about this protein and its source genome.
- Accession
- PA1035
- Gene
- PA1035
- Status
- annotated
- Amino acids
- 164
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
Gene Ontology (GO)
1- GO:0009269 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 38 | 157 | InterPro | IPR013990 | Water stress and hypersensitive response domain |
| 38 | 157 | SMART | SM00769 | why |
| 22 | 26 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. |
| 32 | 158 | PANTHER | PTHR31459 | - |
| 32 | 158 | InterPro | IPR045043 | Late embryogenesis abundant protein Lea14-like |
| 19 | 156 | SUPERFAMILY | SSF117070 | LEA14-like |
| 1 | 21 | SignalP_EUK | SignalP-noTM | SignalP-noTM |
| 1 | 9 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. |
| 1 | 26 | Phobius | SIGNAL_PEPTIDE | Signal peptide region |
| 10 | 21 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. |
| 59 | 153 | Pfam | PF03168 | Late embryogenesis abundant protein |
| 59 | 153 | InterPro | IPR004864 | Late embryogenesis abundant protein, LEA_2 subgroup |
| 27 | 158 | Gene3D | G3DSA:2.60.40.1820 | - |
| 27 | 164 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA1035
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.959 | ||||||
| 4 | 0.247 |