Protein profile

PA1078

flagellar basal body rod protein FlgC

Genome: NC_002516.2

Gene: flgC PA1078 Structure source: AlphaFold UniProt Q9I4Q1
Export view
Amino acids 146
Annotations 4
Features 9
PDB binders 0
Druggability 0.313

Overview

Basic information about this protein and its source genome.

Accession
PA1078
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
flgC PA1078
Status
annotated
Amino acids
146
Structure source
AlphaFold
GO
GO:0009288 A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0030694 The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings. GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria. GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.313
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0009288 A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
  • GO:0030694 The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.
  • GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
  • GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
13 33 ProSitePatterns PS00588 Flagella basal body rod proteins signature.
13 33 InterPro IPR019776 Flagellar basal body rod protein, conserved site
4 82 PANTHER PTHR30435 FLAGELLAR PROTEIN
7 34 Pfam PF00460 Flagella basal body rod protein
7 34 InterPro IPR001444 Flagellar basal body rod protein, N-terminal
98 144 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal
98 144 InterPro IPR010930 Flagellar basal-body/hook protein, C-terminal domain
5 146 NCBIfam TIGR01395 flagellar basal body rod protein FlgC
5 146 InterPro IPR006299 Flagellar basal-body rod protein FlgC

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1078
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.313