Protein profile

PA1084

flagellar basal body P-ring protein

Genome: NC_002516.2

Gene: PA1084 flgI Structure source: AlphaFold UniProt Q9I4P5
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Amino acids 369
Annotations 4
Features 31
PDB binders 0
Druggability 0.508

Overview

Basic information about this protein and its source genome.

Accession
PA1084
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1084 flgI
Status
annotated
Amino acids
369
Structure source
AlphaFold
GO
GO:0009428 One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer. GO:0030288 The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0005198 The action of a molecule that contributes to the structural integrity of a complex. GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.508
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0009428 One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer.
  • GO:0030288 The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
  • GO:0005198 The action of a molecule that contributes to the structural integrity of a complex.
  • GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Sequence Features

Domain/signature hits from InterPro and related databases.

31 records
Show feature table
Start End DB Term Name
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
18 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
3 369 PANTHER PTHR30381 FLAGELLAR P-RING PERIPLASMIC PROTEIN FLGI
3 369 InterPro IPR001782 Flagellar P-ring protein
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
7 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
6 369 Hamap MF_00416 Flagellar P-ring protein [flgI].
6 369 InterPro IPR001782 Flagellar P-ring protein
23 369 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
24 39 PRINTS PR01010 Flagellar P-ring protein signature
24 39 InterPro IPR001782 Flagellar P-ring protein
59 74 PRINTS PR01010 Flagellar P-ring protein signature
59 74 InterPro IPR001782 Flagellar P-ring protein
39 54 PRINTS PR01010 Flagellar P-ring protein signature
39 54 InterPro IPR001782 Flagellar P-ring protein
86 105 PRINTS PR01010 Flagellar P-ring protein signature
86 105 InterPro IPR001782 Flagellar P-ring protein
192 210 PRINTS PR01010 Flagellar P-ring protein signature
192 210 InterPro IPR001782 Flagellar P-ring protein
166 184 PRINTS PR01010 Flagellar P-ring protein signature
166 184 InterPro IPR001782 Flagellar P-ring protein
108 125 PRINTS PR01010 Flagellar P-ring protein signature
108 125 InterPro IPR001782 Flagellar P-ring protein
256 268 PRINTS PR01010 Flagellar P-ring protein signature
256 268 InterPro IPR001782 Flagellar P-ring protein
125 143 PRINTS PR01010 Flagellar P-ring protein signature
125 143 InterPro IPR001782 Flagellar P-ring protein
24 368 Pfam PF02119 Flagellar P-ring protein
24 368 InterPro IPR001782 Flagellar P-ring protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1084
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.508
2 0.341
7 0.297