Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA1105
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: fliJ PA1105
Status: annotated
Amino acids: 147
Structure source: AlphaFold

GO

GO:0009288 A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0003774 Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force). GO:0044781 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0006935 The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

8 GO

Gene Ontology (GO)

8

GO:0009288 A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0003774 Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).
GO:0044781 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
GO:0006935 The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0015031 The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

22 records

Show feature table

Start	End	DB	Term	Name
1	147	PIRSF	PIRSF019404	FliJ
1	147	InterPro	IPR018006	Flagellar FliJ, proteobacteria
1	146	PANTHER	PTHR38786	FLAGELLAR FLIJ PROTEIN
21	141	Pfam	PF02050	Flagellar FliJ protein
21	141	InterPro	IPR012823	Flagellar export FliJ
26	53	Coils	Coil	Coil
6	141	NCBIfam	TIGR02473	flagellar export protein FliJ
6	141	InterPro	IPR012823	Flagellar export FliJ
109	136	Coils	Coil	Coil
5	27	PRINTS	PR01004	Flagellar FliJ protein signature
5	27	InterPro	IPR018006	Flagellar FliJ, proteobacteria
64	85	PRINTS	PR01004	Flagellar FliJ protein signature
64	85	InterPro	IPR018006	Flagellar FliJ, proteobacteria
109	127	PRINTS	PR01004	Flagellar FliJ protein signature
109	127	InterPro	IPR018006	Flagellar FliJ, proteobacteria
87	108	PRINTS	PR01004	Flagellar FliJ protein signature
87	108	InterPro	IPR018006	Flagellar FliJ, proteobacteria
45	62	PRINTS	PR01004	Flagellar FliJ protein signature
45	62	InterPro	IPR018006	Flagellar FliJ, proteobacteria
127	147	PRINTS	PR01004	Flagellar FliJ protein signature
127	147	InterPro	IPR018006	Flagellar FliJ, proteobacteria
1	146	Gene3D	G3DSA:1.10.287.1700	-

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

No pockets are loaded yet for the displayed AlphaFold model PA1105 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1105	AlphaFold	—	—	full sequence	—	Viewing